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Description

Appetite suppression from GLP-1 activation occurs primarily through hypothalamic neurons, particularly in the arcuate nucleus

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Moreover, the magnitude of WL with retatrutide also exceeded that seen with other pipeline multi-agonists such as CagriSema (cagrilintide, an amylin agonist, in combination with semaglutide), mazdutide and survodutide (Fig

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